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Stem Cell

Stem Cell Treatment in India

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Stem Cell Treatment in India

On our planet Earth everyone is born in different ways, some are born in the usual healthy way, while others with certain neuromuscular ailments. The stem cell therapy is the famous, leading and productive treatment option for various degenerative ailments using stem cells. These stem cells can be easily extracted from our bodies and thus have the potential to treat different disorders like neuromuscular and degenerative ailments.

Cells are the basic functional and structural units of all living organisms. Cells are responsible for all the metabolic activities of the body. Stem cells are the building blocks of Regenerative Medicine. Stem cells have the capacity to develop into different cell types in the body, depending on their class of stem cells (multipotent or pluripotent). Acting as a sort of repair system, they can divide themselves to replenish other cells for as long as the person is alive limitlessly. When a stem cell divides, each "daughter" cell has the capacity to either remain a stem cell or become another type of cell with a more specialized function, like muscle cell, a red blood cell, or a brain cell and many more.

Types of Stem Cells

  • Embryonic Stem Cells (ESC)
    • Embryonic Stem Cells are received from Embryos created in vitro fertilization and Aborted embryos, which are derived from a 4-5-day old human embryo that is present in the blastocyst phase of development. Stem cells give rise to multiple specialized cell types that make up the heart, lung, skin, and other tissues. They are the most potential type of stem cells.

  • Umbilical Cord Stem Cells
    • Umbilical cord blood contains hematopoietic (blood) stem cells. Hematopoietic stem cells, obtained from bone marrow or blood, have been used in stem cell treatments for leukemia, blood and bone marrow disorders and immune deficiencies for long time. This type of stem cells originates from the umbilical cord and are obtained immediately after birth. Umbilical cord blood is rich in stem cells and other cellular components like immune cells which ave various benefits. These cells are preserved by Cord Blood Banks now a day.

  • Adult Stem Cells
    • Adult Stem Cells (ASC) are received from Limited tissues (bone marrow, muscle, brain, peripheral blood, skeletal muscle, skin, teeth, heart, liver, gut, ovarian epithelial tissue and testis. It is believed that they reside in a specific area of each tissue called a "stem cell niche". The primary role of the adult stem cells is to initiate reparative mechanisms following organ damage or injury. These cells are not connected with ethical issues so are used for cell-based therapies for a various kind of disorders. Adult stem cells develop replacements for cells that are lost through normal wear and tear, injury or disease. Adult stem cells are capable to divide or self-renew indefinitely, and to generate a wide range of different types of cell from the origin organ and can even regenerate the entire original organ.

How does Stem Cell work?

Stem cells are characterized by two unique properties of self-renewal and regenerate into different cell types. They have the capacity to multiply indefinitely and to produce multiple identical cells. Additionally, acting as a sort of internal repair mechanism, they can multiply themselves limitlessly to replenish any other cells.

  • Stem cells achieve their reparative functions through the following procedure:
    • They can facilitate the release of growth factors which can regenerate and provide healing effect on damaged tissue.
    • They increase the blood supply to the damaged tissue which fastens the repair process.
    • They have the extraordinary ability of regenerating into the specific cell types of damaged tissue.
      The main task of stem cells is to repair and regenerate damaged cells. Stem cell therapy explore this function by monitoring these cells systematically when injected in high concentrations directly into the damaged tissue, where they can advance its self-healing. Most scientists have agreed that stem cell has great life-saving capability and can advance the study as well as the treatment of various diseases and injuries.

(A)They can Multiply infinitely

(B) Stem cells can convert themselves into other cell types

(C) Stem cells release positive chemicals

(D) Stem cells improve blood supply

Procedure of Stem Cell Therapy

Stem Cell Therapy is a detailed treatment plan which is prepared depending on the prevailing medical condition of the patient. Stem Cell Therapy is a minimally invasive non-surgical procedure; therefore, the patients should not take any blood-thinning medication ten days prior to the treatment. However, it is recommended to consult the doctor before discontinuing any type of medication.

The treatment procedure includes:

    • Bone Marrow Extraction
    • Isolation, Analysis and Concentration of the Stem Cells in the Laboratory
    • Stem Cell Implantation
  • Bone Marrow Extraction
    Bone marrow is the soft sponge-like material found inside the bones. The formation of blood takes place inside the bone marrow. Bone marrow are a rich source of adult stem cells. Extraction of bone marrow from hip bone is the simplest source for stem cells. The procedure is usually carried out under local anesthesia and with the help of a bone marrow aspiration needle. This procedure longs for only 15 to 30 minutes. Around 80 ml to 120 ml of bone marrow is extracted, depending on the weight of the patient.

  • Isolation, Analysis and Concentration of the Stem Cells in the Laboratory
    First, the stem cells are isolated. The bone marrow extracted is further transferred to the certified stem cell laboratory for processing, where the density gradient centrifugation method is utilized to separate or isolate the stem cells from the extracted bone marrow. The method separates the Bone Marrow Mononuclear Cells (BMMNCs). BMMNCs are a heterogeneous mixture of cells which include hematopoietic (lymphocytes, monocytes, stem cells and progenitor cells) and non-hematopoietic cells (mesenchymal stromal cells, endothelial progenitor cells – EPCs, etc.). The separation process takes around 3 to 5 hours. Each sample is also tested for the presence of viral markers such as HIV, hepatitis B and C. Once more than two million CD34+ cells with over 80 percent viability are obtain, the stem cell concentrate is approved for patient’s treatment.

  • Stem Cell Implantation
    The patient's condition determines the method of stem cell implantation. There are different ways of administering stem cells:

    • Intravenous administration:
      • Catheter using angiography
      • Direct injection into the target area
      • Retrobulbar Injection

    Once the BMMNCs are separated and purified (about 3-4 hours). The stem cells are first diluted in the cerebrospinal fluid (CSF) and administered intrathecally (injected into the fluid around the brain and spine) using an epidural needle or a spinal needle. In certain cases, where stem cells are to be injected into the muscles (example. Muscular Dystrophy) the stem cells are diluted in the CSF and then injected into the muscles with the help of a very thin needle.

Procedure after Stem Cell Therapy

The stem cell therapy must be followed by an intensive neurorehabilitation process which includes physiotherapy, occupational therapy, aquatic therapy, creative visualization, yoga therapy, counseling and specialized diets. Stem cell therapy must be followed by a proper rehabilitation regime to gain a proper positive response. The rehabilitation therapies enhance the mobilization of stem cells and aid in the regenerative and reparative process. This holistic approach helps the patients to lead a better quality of life.

Safety Measures

  • Adult stem cell therapy is a safest method of treatment. There have been no cases of serious adverse events or neurological deterioration due to stem cell therapy as per all the publications worldwide. However, in some cases minor reversible symptomatic procedure related problems occasionally do occur which are treatable with no long-lasting side effects.
    Absolutely safe
    Zero Rejection
    Easily Available
    No Ethical Issues

Application Area of Stem Cell Therapy

  • Rheumatoid arthritis
  • Motor Neuron Disease
  • Cerebral palsy
  • Down’s Syndrome
  • Duchenne muscular dystrophy
  • Mental Retardation
  • Spinal cord injury
  • Sports injuries
  • Diabetes type 1 and 2 and complications
  • Muscular Dystrophies
  • Parkinson’s disease, Autism
  • Epilepsy
  • Neurofibromatosis / Optic Glioma
  • Cosmetic Enhancement
  • Multiple sclerosis
  • Complete Body rejuvenation

Total Stay in India and Cost Estimate

The patient has to stay for 30 days, however in some cases 45 days of stay is recommended. The approximate cost of Stem Cell Treatment would range between USD 6500 to USD 10000 per cycle depending on current condition of the patient and facilities.

Why MedicoExperts?

At MedicoExperts, we understand the significance of your health, well-being and importance of leading an independent life. Our aim is to provide you the best experience for Stem Cell treatment in India at our top associate hospitals in India. Your Believe and trust of on us is our responsibility. For your privacy and protection, we maintain a strict non- disclosure policy. We understand that while you choose to travel abroad for your Stem Cell Treatment, you would surely look for positive results, comfort and guaranteed result. We would also provide you end to end assistance for your medical trip to India and shall provide complete solution for your Stem Cell Treatment – right from assisting you with the visa, hotel arrangements, airport pick up and drop, inland transfers, money exchange or sight-seeing and all other concierge services. We thus assure you hassle-free arrangements for evaluations, treatment, stay and travel in India. For more information and getting a tailor-made treatment plan for your stem cell treatment in India, please mail us your details and medical history at enquiry@medicoexperts.com Our concern person would get in touch with you according to your convenient time to guide you with all information regarding your treatment.